Both alcohol-dosed and placebo-dosed participants are breath-tested after they have completed their required dose. Those receiving placebo receive the same total quantity of beverage as those receiving alcohol. Eligible participants report back the next week for their first dosing night where they receive several drinks (alcohol or placebo) sufficient to raise their Breath Alcohol Level (BrAC) to 0.10 g% the amount of beverage administered is based on their body weight. Participants report to the study site on the first session for an additional screening by the study physician and go through the informed consent process. Eligible volunteers receive written instructions regarding participation and are scheduled for the study sessions. Prior to enrollment, volunteers are screened to ensure they meet initial eligibility criteria. Participants are undergraduates who volunteer and meet inclusion criteria. Participation involves a total of five sessions over a two week period. This design is intended to test the hypothesis that intoxication (0.10 g% BAC) with alcoholic beverage impairs next-day academic performance. The procedure is conducted twice with one week in between, switching the individuals' dosing status, presenting a different, but comparable lecture and reading, and administering a different quiz based on the new lecture and reading and a different, but comparable standardized achievement exam. We are also collecting information on hangover symptoms and sleep quality the morning after dosing, in addition to participants' self ratings of academic performance. Data on participants' demographics, family history of drinking problems and alcohol use. Participants' cognition is tested using the the Psychomotor Vigilance Test (PVT). The morning after dosing, participants' academic performance is measured using a standardized achievement test (Graduate Record Exam). Participants are dosed on two separate occasions, once with non-alcoholic beverage and the other time with alcoholic beverage sufficient to raise blood alcohol to 0.10 g%. A placebo-controlled 2-period crossover design will be used to compare the effects of dosing status on academic performance, with participants serving as their own controls. The primary goal of the study is to assess the effect of heavy drinking on next day academic performance. Why Should I Register and Submit Results?.
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